Posted by JohnL on August 31, 2000, at 5:15:06
In reply to Polypharmacy, posted by ash on August 31, 2000, at 0:06:24
Just a gut instinct...
You could maybe order some Adrafinil and Amisulpride. Try them one at a time or, as I've discovered, combine them.
I offer this suggestion because I too suffered from the same anhedonic type depression you so accurately described. And like you, none of the available meds in any kind of combination worked very well, and often just made me worse or made me numb or made me a walking reservoir of side effects. I've been on as many as 5 or 7 meds at the same time, including all of the ones you mentioned.
Adrafinil worked somewhat on my anhedonia. Amisulpride did too. Both give you a different feeling however. But when the two are combined, the end result is so much more than the sum of the two added together. I turned to overseas meds after being totally frustrated with the slow and fruitless procedures of USA psychiatrists. In some ways I think they are seriously handicapped by not using some of the other meds from around the world. Some of those meds are far superior to anything we have in the USA.
For me anyway, the ONLY meds in the WORLD that really worked on my stubborn longterm anhedonia are Adrafinil+Amisulpride. And side effects are practically zero. For that reason, I offer the suggestion that you try this too. Overseas ordering is kind of uncomfortable at first, but that becomes routine and miniscule in comparison to how well you might end up feeling. If after all this there is no progress, then you can always at any time go back to your psychiatrist and pick up where you left off. Hopefully though, that will be a bridge you never have to cross again. :-)
Your depression and mine sound very much alike. Adrafinil+Amisulpride is worth considering, since it has been so successful for me. I would not be suggesting this if your depression was of a different type. But when prominent anhedonia is involved, I know what works and what doesn't. I do not know any drug your psychiatrist could prescribe that will work for your symptoms. But I do know of two European drugs prescribed by European doctors that could very well work. The cool thing is, you don't need to actually go to Europe and you don't need to see a doctor. You've been around meds long enough to know how to be able to manage this with or without a doctor's blessings.
John
poster:JohnL
thread:44126
URL: http://www.dr-bob.org/babble/20000822/msgs/44139.html