Posted by JohnL on August 18, 2000, at 4:50:54
In reply to Re:JohnL - THANK YOU!, posted by Anna P. on August 17, 2000, at 16:18:58
Yours is a frustrating story to hear. I mean, even Revia pooped out? That's the one, you know, that is supposed to prevent poop-out. But it pooped. Yikes. Not sure what to make of that. Except that since you did have a good response for several weeks, that indicates there was some involvement of the opiate system. If you ever wanted to return to Revia for a second try, I have heard that doses up to 100mg are sometimes used. 50mg was not the highest. Some people need 100mg.Anyway, not much to add here. Just babbling. You asked what's going on with me? I'm doing fine for the first time in many years. On a 1 to 10 scale I'm about a 9. For the last 10 years I've bounced between 1 and 4. My magic potion is:
300mg Adrafinil
25mg Amisulpride
200mg SAM-e
7.5mg RemeronI too responded well to Revia at first, but then it faded. I wonder if our chemistries are similar. But then again, I responded badly to Reboxetine. So maybe we're not that similar. I came to realize I was actually suffering mainly from one powerful symptom of depression--anhedonia. Only my current cocktail has been successful in treating that primary symptom. Strangely, not one of the ingredients alone was all that effective. But miniscule amounts of all of them combined must work in some exaggerated synergistic way, because it sure works. But I admit, it's taken a lot of tweeking, fine tuning, and experimentation to get here. Strangely too, higher doses were not as good. Only when I started lowering doses did I get better.
This is all in agreement with ideas I have come to believe--ideas that are somewhat in contrast to generally accepted psychiatric principles. That is:
The closer a med or cocktail is to treating the real underlying problem, the smaller the dose is needed. When a med is farther away from the real problem, there is a chain reaction trickle down effect--versus a target bullseye--that requires higher doses.
The closer a med is to the real problem, the fewer the side effects.
The closer a med is to the real problem, the faster the results.
The closer a med is to the problem, the more complete the response.I'm cheering for you. I want your next experimentations to hit a bullseye!
John
poster:JohnL
thread:42844
URL: http://www.dr-bob.org/babble/20000811/msgs/43223.html