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Re: CPK level increase - antidepressant dystonia ? » Sunnely

Posted by SLS on July 21, 2000, at 9:31:40

In reply to Re: CPK level increase--CamW?????, posted by Sunnely on July 19, 2000, at 0:22:25

Hi Sunnely.

> Some of the newer antidepressants have the potential to cause elevation of muscle CPK since they are capable of inducing dystonic reactions such as neck stiffness (torticollis) and back/trunk stiffness. The potential for drug-drug interactions between serotonin-boosting antidepressants and other serotonin drugs may lead to serotonin syndrome which may also cause some elevations in muscle CPK but usually not as high as NMS.

Which of the "newer" antidepressants are capable of causing dystonic reactions? What mechanisms might be responsible for this?

Also, out of curiousity, are there different types of CPK depending upon the type of muscle it originates from?

It is so tempting to ask you a trillion questions. I apologize.

Thanks.


- Scott

 

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