Posted by SadSuzie on July 6, 2000, at 7:22:16
In reply to Re: Stim/Sulp. Question-AndrewB,SLS,JohnL,etc, posted by KarenB on July 5, 2000, at 22:42:02
Hey Karen,
Actually, I do think I have a brain very similiar to yours - at least in regard as to how they react to different medications. Please keep posting your med combos and results. Definitely let me know if you find a source for amisulpride.
Thanks,
ss
> > Thanks for the info. about the consultant saying greater binding affinities may hobble the effectiveness of amisulpride. Could you ask what the implications of this may be for those who take amisulpride; 1) more non-responders vs. Sulpiride 2) a less robust effect 3) a greater chance of postsynaptic instead of presynaptic antagonism at low doses.
>
> Hey guys,
>
> You know, when you get into that binding, postsynaptics, presynaptics, etc., you kind of lose me. I'm just not that technical. So, please respond accordingly, OK? OR...write a really long one explaining that stuff?
>
> Question: Does the above question indicate that there may be a substantial difference in expected response between amisulpride and sulpiride? If so, why?
>
> As you know, I did best on Amineptine/Sulpiride. Both are Dopamine reuptake inhibitors right? At what receptors? What then would this indicate about possibilities of successful medications for me? Do you think Adrafinil is a good choice...or only good if augmented by another Dopamine blocker? It seems to me it would enhance the energizing effects of the Adrafinil. Is there another psychostimulant that is a Dopamine blocker to replace the Amineptine? Ritalin and Adderall just do not compare to the Amineptine.
>
> What would you do if you had my brain (aside from considering a sex change)?
>
> Sorry for the deluge of questions but I plan to order one or the other soon and want to make the right choice.
>
> BTW, anybody got any amisulpride laying around that you won't be using?
>
> Thanks!!
>
> Karen
poster:SadSuzie
thread:39176
URL: http://www.dr-bob.org/babble/20000630/msgs/39537.html