Posted by Rick on June 22, 2000, at 16:09:56
In reply to side effect with provigil, posted by shellie on June 21, 2000, at 10:17:22
> I have had a loss of appetite with provigil
(which is okay), but I also feel some nausea,
which is not okay. I've been taking it about 5 or
6 days now. First, has anyone else experienced
this? Second, if you have, has it gone away over
time? Thanks. ShellieI had very mild nauesa the first few days. But
then, this is one side effect that doesn't seem
to hit me as hard as it hits many people. (And
I'm talking about many different meds that can
casue nausea,not just Provigil -- e.g., Celexa,
Serzone). As with AD's that cause nausea, my
readings suggest that among *most* people who
experience nausea with Provigil, it eventually
goes away or becomes very mild. The nausea can
disappear pretty suddenly at some point, or it can
be a gradual improvement over two-four weeks.A couple more thoughts:
-- If you're not already doing so, take the
Provigil after a meal. This could certainly help
reduce nausea. Taking it after a meal delays
absorption by about an hour, but does not reduce
the amount or duration of beneficial effects in
any way.-- I assume you started low...certainly no higher
than 100 mg. If you did start at 100, then maybe
you should cut back to 50, or even 25. Then,
building up slowly to your optimal theraputic dose
(usually 200, but 100 might work) could reduce
nausea and any other side effects as your body
gradually acclimates to the Provigil.Finally remember that while some wakefulness
should be apparent very soon, other beneficial
effects can take longer -- e.g. Provigil's
antidepressant and mood-brightening effects
usually take 5-10 days at a theraputic dose. I'm
not sure I buy into this one, but a "good drug"
guide says memory-enhancement kicks in after about three months. (Cephalon IS currently testing
Provigil for use in Alzheimer's and ADHD.)Hope this helps,
RickP.S. If you or Karen do end up with Adrafinil
instead of Provigil, be
poster:Rick
thread:37987
URL: http://www.dr-bob.org/babble/20000619/msgs/38137.html