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Re: Scott

Posted by AndrewB on June 12, 2000, at 15:55:51

In reply to Re: MAOIs and Amisulpride: Thank You Michael!, posted by SLS on June 11, 2000, at 12:55:48

Scott,

I haven't found entacapone to be very useful by itself. That shouldn't be surprising as it only generates a 30% COMT inhibition. Soon I will combine it with Sinemet (l-dopa +) to see what happens, and after that probably throw selegiline into the mix. There are couple other combo.s I might also try. If one of the combo.s is effective, I will then try to figure out if it is safe to use long term. Anyway I will of course let you know how it goes.

I am currently giving naphazoline a trial (See the above post entitled 'For those interested in reboxetine or adrafinil'). Naphazoline seems to me to be a perfect diagnostic tool to determine if a person would respond to some NE active drug such as adrafinil. Imagine if one of the first things a psychiatrist did with a patient was to administer naphazoline eye drops! I'm trying now to see if I want to keep using naph. over the long term.

I also tried Mirapex at 5mg./day, as the latest study indicated this was the most effective dose. I had already once before given it a trial at a much smaller dose. It was a failure. This time at 5mg. Mirapex still didn't substitute (at all!) for amisulpride. I think I took the Mirapex for four days at 5mgs. before I stopped the amisulpride. Two days later, CRASH! The depression and anxiety came rushing back. So I quickly restarted the amisulpride. So what do you think. Why doesn't Mirapex help me at all?

AndrewB


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Psycho-Babble Medication | Framed

poster:AndrewB thread:36914
URL: http://www.dr-bob.org/babble/20000610/msgs/37070.html