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Re: AD's and Dopamine Agonists? johnturner:

Posted by KarenB on May 31, 2000, at 16:45:14

In reply to Re: AD's and Dopamine Agonists? What to try next, posted by JohnL on May 17, 2000, at 3:56:00

Hey John,

I'm really late responding to this, so I hope you're still around. I am the woman with ADD/hypoactivity of whom you speak in your inquiry.

Ditto everything JohnL said. If you want to try overseas meds, Adrafinil combined with Amisulpride would be my first suggestion. I used an antidepressant while I lived in the Philippines (Amineptine), along with a drug similar to Amisulpride, called Sulpiride. It was the bomb. I have never felt so good in my life, in a non-medicated sort of way. However, Amineptine, (a psychostimulant modified tricyclic) has since been discontinued worldwide. Sigh. So, I sought to find something stateside to replace this very effective combo.

I do not do well at all on SSRIs.

I am currently on Adderall (an ADD stimulant) and Buspar (an anti-anxiety med with some anti-depressant qualities). I am taking 10mg Buspar three times a day and 20mg Adderall 1/2 hour before getting out of bed in the morning, then 5-10 mg five hours later. I started the Adderall at 10 mg twice a day but have since adjusted the dosage. It takes a while to find exactly how long it lasts in your system so you can take the second dose BEFORE your mood and energy start to decline.

The Buspar doesn't work for everyone but my doc said that it is effective sometimes in low level depression like mine (Dysthymia). This time, he was right and it has worked just fine. Just the stimulant alone does not do the whole job for me - I have the energy but no desire.

BTW, I take Propranolol (Inderal - a beta blocker) to prevent migraines which are triggered by the stimulant. I don't like taking so much medication but you gotta do what you gotta do.

Karen


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