Posted by Cam W. on May 18, 2000, at 13:01:31
In reply to Re: Cam--Serotonin-modulated pathways?, posted by medlib on May 17, 2000, at 21:02:28
medlib & all - The serotonin pathways that are broken down (or disinhibited) are as follows:
Serotonin neurons from the midbrain raphe nuclei to:
Prefrontal Cortex (higher mental activities) - Depression.
Limbic System (incl.limbic cortex and hippocampus) (arousal & motivation) - Panic Disorder.
Basal Ganglia (movement, motor circuitry) - OCD.
Hypothalamus (sugar & fat metabolism) - Bulemia.
These serotonin pathways (between the midbrain raphe nuclei and above structures) are thought to be involved in the above disorders. It is more complicated than this, involving other neurotransmitters and hormones, but this does show serotonin's involvemnet in these disorders.
Thanks for the article medlib - Cam
poster:Cam W.
thread:33678
URL: http://www.dr-bob.org/babble/20000517/msgs/33902.html