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Re: Mirapex vs. amisulpride

Posted by AndrewB on April 21, 2000, at 11:12:50

In reply to Mirapex vs. amisulpride, posted by DC on April 20, 2000, at 18:31:06

> Could someone tell me the difference if any between mirapex and amisulpride? Any reason to prefer the latter over the former? Thanks, Dwight

Dwight,

Without getting into details, both meds act pretty much on the same dopamine receptors in the brain but they go about it different ways. Choosing between the two drugs can be based on several criteria. Let's compare:

Amisulpride has been extensively studied for depression and is well proven. There are only 3 or 4 small studies that have been done on Mirapex for treating depression but the results of the studies were promising.

Amisulpride is commonly used for depression in parts of Europe. Mirapex, at the present time, is only rarely used for depression.

Amisulpride must be ordered from overseas (with or without a prescription) while Mirapex is available in the US. I have produced an information piece on amisulpride that can be shown to one's psych. in order to obtain a prescription. Email me at andrewb@seanet.com and I will send it.

Amisulpride costs about 60 cents per dose while Mirapex costs usually over a $1.50/dose. But Mirapex's cost, being available in the US, may be covered in part by insurence.

Amisulpride very rarely has side effects in men but 5% to 10% of women using amisulpride will quit using it due to endricrinological side effects like missed menses and breast swelling. Mirapex will cause nausea and headaches at first, sometimes severe, but these side effects will pass.

AndrewB


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