Posted by michael on April 19, 2000, at 3:47:53
In reply to Re: Provigil, Adrafinal, and Amisulpride, posted by JohnL on April 19, 2000, at 3:13:06
Hey JohnL-I tried it, and I was out like the proverbial light bulb - slept 12+ hours/day.
However, it just recently occured to me that I still had prozac in my system (had been taking 20mg/day) while I was trying the amisulpride - I had almost no wash-out period between the meds. Think it might affect me differently now, w/o the prozac in my system? I'm planning to give adrafinil a shot, begining tomorrow... anyway, thanks again... michael
> > Reading over the posts here, I am getting enthusiastic about these three new drugs.
> > 1. Is provigal the same thing as modafinal, and why is it only being used for narcrolepsy? If it has AD effects?
> >
> > 2. Are these three drugs all in the same class? Are they all stimulant type drugs?
> >
> > 3. Which one do you think would be most likely to help someone with a combination of anhedonia, inattentive add, and social phobia?
> >
> > I'm sorry I can only ask questions at this point. Any help would be greatly appreciated. Thanks, Dwight
>
>
> Yes, Provagil is Modafinil. Though its designated use is in narcolepsy, it has shown promise in other conditions as well. I think all drugs do actually. For example, Zyprexa for depression or mood stability, not just schizophrenia. Lamictal for depression and mood stability, not just epilepsy. Prozac for OCD, not just depression. On and on. Etc.
>
> Modafinil and Adrafinil are technically psychostimulants, though their profiles are quite different (more subtle, smoother, takes longer) than typical stimulants. Amisulpride is a European antipsycotic technically. But it is somewhat alerting, not often sedating.
>
> For your symptoms, I personally feel any one of these could work better for you than the SSRIs or other standard antidepressants. That's my personal experience anyway. SSRIs and stuff seem pretty effective at relieving depression, but they often don't affect a few core symptoms. Anhedonia seems to be a most stubborn condition, which I think responds better to NE drugs like Adrafinil or Modafinil (or tricyclics), and dopamine drugs like Amisulpride.
>
> I think Adrafinil is worth trying first, because it is easy to get without a prescription, and it's fairly cheap. Modafinil can also be found without a prescription from overseas, but it is very pricey...more so than what you are used to paying for any other psychiatric drugs. Amisulpride requires a prescription, regardless of where you get it, 50 tabs of 200mg are a little over $200. But at 50mg to 100mg a day normal dosage, those 50 tabs will last 100 to 200 days. So the expense isn't too bad, but actually getting it is not as easy as Adrafinil.
>
> I've tried Amisulpride alone, Adrafinil alone, and the two combined. Amisulpride provided amazing social comfort, relaxation, and confidence. But it did little for anhedonia. Adfrafinil is great for both social phobia and ADD and depression, all in one. So again, I tend to lean toward Adrafinil as your first, easiest, and cheapest choice. I am taking both Adrafinil and Amisulpride. Though I'm not 100%, I'm way better than on any of the dozens of antidepressants and things I've tried over the years.
> JohnL
poster:michael
thread:29957
URL: http://www.dr-bob.org/babble/20000411/msgs/30537.html