Posted by M on April 4, 2000, at 7:25:55
In reply to Re: Stimulants, posted by N on April 4, 2000, at 0:43:53
> > > I'm sure others can give you more informed advice, however it occurred to me, since Trazadone is a serotonin agonist and you had such luck with it in the past, perhaps you could try Trazadone again in combination with a med. known to prevent SSRI poop out, such as pinoldol (spelling?), naltrexone, or bromocriptine. Another possibility is trying another serotonin agoninst or 5htp.
> > >
> > > AndrewB
> >
> > Thanks, Andrew, that's helpful. I'll do a little research on these drugs and see what might make sense.
>
> Maybe moderately high doses of B complex and a good multivitamin might help. Also, try not to get too much sleep. There is a limit to what medications can do.I do take a multivitamin every day so it's certainly easy enough to add B complex.
As far as sleep is concerned, "lack of" is a much bigger problem than "too much." Yes, I do sleep at night, but generally it's not more than three or four hours and, even then, I'm restless and don't sleep very soundly. I very rarely sleep during the day. That was one area where Trazodone helped tremendously. It allowed me to fall into a sound sleep quickly and easily and stay that way for 7 to 8 hours, and I'd awake feeling refreshed and energized.
The main problem seems to be lethargy and lack of motivation. I feel absolutely immobilized, sometimes not leaving the house or talking to anyone for weeks at a time. The smallest things seem a major effort, like getting showered and dressed, and most times I just don't care. That's why I thought a stimulant might be useful in addition to the Wellbutrin I'm currently taking.
In doing some research yesterday, I also ran into another bid of info that may or may not be relevant. I've been taking Toprol XL for quite a long time and cannot discontinue it; however, some of the side effects of beta blockers can be fatigue and depression. I don't quite understand the mechanics of it, but apparently it blocks something that can cause levels of something else to drop which, in turn, can cause or contribute to depression. The solution, then, is to find the specific drug that will counter these effects. From what I read, bromocriptine could be one of them, but I have much more research to do.
Anyone heard this about beta blockers, the exact mechanism at work that may cause depression, and/or what drug might counter the specific negative effect?
poster:M
thread:28737
URL: http://www.dr-bob.org/babble/20000401/msgs/28812.html