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Re: Anti-psychotic meds

Posted by JohnL on April 1, 2000, at 2:34:26

In reply to Anti-psychotic meds, posted by SusanJane on March 30, 2000, at 14:52:42

> I'm interested in locating an article or information comparing the different anti-psychotic medications. I've been told that Sulpiride has much less of the dulling effects then the others (Mellaril, etc). Thank you for taking a moment to answer my plea.
>
> SusanJane :)

Olanzapine (Zyprexa) is probably the safest of them all, and easy on side effects. Its sedation is good for sleep, but doesn't carry over much into the next day after a couple days of adjustment. It has a good antidepressant antianxiety effect, either as monotherapy or in combination with an antidepressant. Common side effect is weight gain. Risperdal is a bit less sedating and less weight gain, though a tad less safe. Stelazine is more alerting. It is the closest thing to Amisulpride available outside of Europe.

But of them all, I think Amisulpride gets top honors. It is effective at low doses for negative symptoms, dysthymia, and depression. At high doses it is for psychosis. At medium doses it's kind of a mix. So it's highly adjustable. And it's very specific for dopamine receptors. Most other antipsychotics have action at multiple receptors other than just dopamine. It's a real crime this one isn't available in USA. Thank goodness for European pharmacies willing to accept a USA prescription and mail it.


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