Posted by Scott L. Schofield on March 22, 2000, at 9:44:49
In reply to Re: Trazadone + Effexor danger?, posted by Cam W. on March 22, 2000, at 6:46:30
It sounds like the pharmacist is being cautious. But if your doctor prescribed, it's probably best to follow his/her instructions. I've heard of people taking larger doses of Traz with Effexor, and also larger doses of Serzone (a close cousin of Traz) with Effexor.
>
> Serotonin syndrome is always a risk when we mix multiple serotonin medications. Infrequently it's even a risk on just one drug. As with any other approach, it might be a good idea to start low and go slow until you have a better feel for how you will respond to these meds.
I have even seen quite a few reports of serotonin syndrome occurring as the result of combining lithium with an SSRI. Lithium has been purported to enhance serotonergic neurotransmission via postsynaptic second messenger systems. Many investigations have demonstrated this using various methods.
- Scott
poster:Scott L. Schofield
thread:3318
URL: http://www.dr-bob.org/babble/20000321/msgs/27838.html