Posted by AndrewB on March 2, 2000, at 14:14:30
In reply to Re: question to JohnL, posted by SIGOLENE on March 2, 2000, at 11:01:43
> Thank you John for your answer,
>
> In fact I already in the past tried tricyclics AD which acts only on NE. There was an improvment for a while. But I had to stop these meds because I fall asleep during the whole day. And anticholinergic drugs are not good for me due to urinary tract chronic infections. (yes anticholinergics have also an effect on that ! It's contracting this muscle). I would like to find a tricyclic, no anticholinergic, and not too sedating, wich acts only on NE. But untill yet I couldn't find this product. The non- anticholinergics ones are all acting on NE and 5HT. That's why I was asking my first question of this thread. Do you have an idea? An did you know that anticholinergics drugs were also bad for memory ?
> In your answer, please talk about the substance not the brand names of drugs, because in Europe the brand names are different for the same product.
>
> Thanks SigoleneSigolene,
Are you considering reboxetine. It think it is available to you in France. In studies it was shown to be more effective in general than desipramine. It is considered the cleanest of the NE active med.s. It tends to increase motivation and energy rather than be sedating. That has been my personal expereince. It does have some alpha-adrenergic affinty though meaning it tends to tighten the muscle around the urinary tract making it difficult to urinate. This side effect does not go away but can be countered by an alpha-andrenergic blocking agent such as tamsulosin HCL.
Didn't you say you have chronic fatigue? Have you been diagnosed with that? Have you gotten any blood tests to determine the underlying problem?
poster:AndrewB
thread:25205
URL: http://www.dr-bob.org/babble/20000302/msgs/25501.html