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Re: Reboxetine - Nobody loves me any more.

Posted by Leighwit on March 1, 2000, at 16:00:11

In reply to Re: Reboxetine - Nobody loves me any more., posted by Cam W. on February 29, 2000, at 16:25:04

Scott,

I hesitated to respond because I was a very short-term Reboxetine "starter". Discontinued after only 3 1/2 weeks.

I've been on ALL of the SSRIs, (Prozac, Zoloft, Paxil, Celexa etc.) plus Effexor, Norpramin, Serzone, Wellbutrin, Ritalin (as an augmentation -- I'm not ADD), Dexedrine, and Aricept (another augmentation).

I had high hopes for the Rebox and went through a lot to get a prescription through a US doctor who would monitor it.

It made me so irritable I couldn't tolerate it. I went down to only 2 mg/day and the relief from the agitation was only minor. I'm a great Mom -- and found even my reactions to my child (let alone my husband!) unacceptable. I could have put up with the stomach side effects (which were pretty tough -- worst of the drugs I've been on), but the irritability just wasn't worth it. I'd feel so uptight (and I do well with stimulating ADs. I don't do well with "calming" ones!!) that I thought I was going to have a heart attack, and I'm someone who has routinely average to low blood pressure levels!

I'm not sure that I would have shared this if it were imminent (and I for one do not think from the sounds of it that it is -- "another" study takes time and money and the results will again be subject to analytical scrutiny which could lead to same labeling issue.) that it would be on the market in the US sometime soon.

But for people who are "waiting" in lieu of trying other drugs, perhaps this perspective will remind people that there doesn't appear to be a record-breaking panacea of any kind on the horizon yet. There are a few people responding extremely well to Reboxetine in Europe. BUT they are not statistically as significant as the respondent efficacy levels of other drugs studied by the FDA over the past ten years or so.

On the other hand, who cares about statistical significance if you are one of the few that it works very well for? (I DO understand that feeling -- which is exactly why I tried it.)

LW


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poster:Leighwit thread:24263
URL: http://www.dr-bob.org/babble/20000220/msgs/25223.html