Posted by Cam W. on February 20, 2000, at 17:36:46
In reply to pharmacokinetics, posted by lois on February 20, 2000, at 16:44:50
> I tried to access this"link" and it said the page was "eaten"
> It listed specific percentages of neurotransmitters affected
> by just about all the AD's.I know it is not all that simple,
> but might help me in search of better mix of AD's.
> MIT.edu said that person might no longer be there.
> Does anyone know how to obtain this page info?
> Thanks.
> LoisLois - The reason you may not be able to find the resourse you are looking for is , that if it was written over a year ago it is probably archaic. Neurological/neurochemical research is advancing at such a breakneck speed, the researchers are even having a tough time keeping up with each other. The brain is a very dynamic and plastic organ and saying (for example) that serotonin, dopamine, noradrenaline, GABA etc., changes will resolve depressive symptoms is very reductionist thinking. Many other chemical pathways are interlinked to the neurotransmitters system. Kinda like how a car works. You cannot built a car by reading the owner's manual, and this is essentially the stage we at at in neuropsychiatry. We need to read past the generalities of the bigger picture and try to see how that bigger picture is affected by the parts we we cannot see. We also need to know how those unseen parts are affected and affect further unseen part (ad nauseum) and finally see what effect these interactions have on the person as a whole. We know that by increasing serotonin in the synaptic cleft between nerve cells seem to improve some of the symptoms of depression. This is a bandage, not something that is attacking at the root of what is depression. Your questions open cans of worm to which can only put some worms back in, the majority of the worms are still out of our grasp. Sorry, that was a little involve. If you have any questions, I will try to help you as much as I can. Remember, always divulge tratment medication changes to your primary health care giver (esp.doc) before striking out on your own in changing your medications. Work closely with him/her (and your therapist & pharmacist) to make sure everyone is in the same page in your treatment regimen. Hope this will help you some. Good luck - Cam W.
poster:Cam W.
thread:22754
URL: http://www.dr-bob.org/babble/20000220/msgs/22766.html