Posted by Cam W. on February 18, 2000, at 20:58:50
In reply to Re: Should have mentioned this is about Luvox advice, posted by Noa on February 17, 2000, at 18:48:00
> You guys...I love the sick humor.
bob - I don't know if this fits in, but I have read several articles stating that nortripyline loses its efficacy during maintainance therapy (a poop-out kind-of-thing). We had several long term nortriptyline users who were decompensating and the dose kept being raised.(eg both were at 175mg nortriptyline at bedtime). One we put on Celexa and Clozaril for a very refractory, psychotic/suicidal depression and he is now functioning at the best level I have seen him in years. The other was switched to Effexor (with some seriously debilitating side effects for 2 weeks) and by the time we got her to 300mg XR once in the morning, she was out of the house, going downtown by herself and actually smiling sometimes. It makes you wonder about notriptyline over the long-term. Nortriptyline had remitted both these people initially and they were remitted for about a year to two years, each. This isn't proof of loss of efficacy, but it has me wondering. (Could have been wrong antidepressant for these people over long-term; disease course changed; could be due to their body's physiology changing or many other factors.) I just thought I'd throw my $.02 in. - Cam W.
poster:Cam W.
thread:21871
URL: http://www.dr-bob.org/babble/20000209/msgs/22338.html