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Re: Reboxetine...(this year, maybe)

Posted by Anon on February 15, 2000, at 6:43:55

In reply to Re: Reboxetine...(this year, maybe), posted by jeff jarret on February 14, 2000, at 13:17:10

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> > Sorry, I won't go into specifics because the issue could be resolved (in which case it is a non-issue) or P&U will not launch (in which case it is also a non-issue).
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> Anon you really dont know the specifics do you.

Actually, I do.

I also am an employee of Pharmacia & Upjohn, and do not wish that to be jeopardized. Revealing more could do just that.

I will say that there are two separate issues at work -

The efficacy issue (discussed on this board) where Reboxetine and Prozac both were found to be no better than placebo - probably due to a poorly designed study or unbelievable bad luck.

Then there is the safety issue, where an unexpected side effect appeared in a handful of patients undergoing trials. This side effect did not appear in testing or actual clinical use in Europe, and is probably due to bad luck - all side effects during trials must be reported, whether or not the drug caused them...the FDA suggested regular testing for this side effect for those taking the drug. P&U felt this would cause most docs to not even prescribe the drug.

I know it is frustrating to those wanting more, but look at it from my point of view - would you put your job in danger to please a few souls you have never even met?

Anon


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poster:Anon thread:21103
URL: http://www.dr-bob.org/babble/20000209/msgs/21569.html