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Anti-Hangover (re: what happens neurochemically..)

Posted by michael on February 10, 2000, at 12:50:27

In reply to Re: What happens Neurochemically during a Hangover, posted by carter on February 8, 2000, at 20:38:57

> Janice,
>
> Luckily, I can no longer drink because of confounding medical conditions, but I must say that when it was okay for me to drink (during the last 3 years), the days following were very dreamy. I felt on top of things; I frequently had sufficient positive mood and energy upon waking up to hop out of bed and immediately start the day. Typically that atypically pleasant, calmed mood would last until 'the day after' had just faded to dusk, at which time I'd usually get a an early drowsiness and a little more depression than average. Perhaps we have problems with sleep latency? Oh, to wake up happy.. I'm hoping Serzone will help.
> Good luck,
> Carter
>
> > the best I have felt (other than mania) has been during hangovers.
> >
> > I no longer drink since I've started medications about 5 years ago. But before this time, I felt the best when I was hung over. As long as, of course, I wasn't nauseau or had a headache.
> >
> > While hungover I had no anxiety, I felt calm, connected to people, stable and had a good sense of well being. Exactly what I've been trying to achieve with less luck with medications.
> >
> > I used to drink probably 5 times a week, socially. I was young and having fun. I'd feel my alcohol after about 2 drinks due to my small size. I would rarely drink over 5 drinks a session, and I usually drank red wine. I would drink both as an upper and as a downer, to party and to relax. As I aged, I drank more to relax and less to party. My drinking always remained in a social context (probably due to sheer willpower).
> >
> > ONce I started Paxil - which threw into a hypomanic state and then promptly stopped working - I completely lost my cravings for alcohol and have barely touched alcohol since then.
> >
> > Any ideas about what happens neurochemically during a hangover, and how I could duplicate that feeling with medications? I have both manic depression and ADHD. I take lithium and Dexedrine.
> >
> > Thanks in advance, Janice.

Janice & Carter:
Before reading your posts, I hadn't seen the cause & effect relationship... but now that I look back over the past month or so, I notice the same thing. I had been going out on Saturday night - late, and drinking, and expecting to be tired (or worse) the next day - hungover.

But each of those Sundays I felt really good - better than usual, good sense of well being, relaxed, comfortable, positive mood, even energetic - "Anti-Hangover". Like you said, Janice, "Exactly what I've been trying to achieve with less luck with medications."

I kept thinking "finally, the meds are starting to kick in". But it never lasted past Sunday - always back to the usual.

If anyone has any ideas, explanations, or insights, (or guesses!) as to what's going on, I'd love to hear them. Seems so counter-intuitive. (daily meds are one thing - daily drinking... not so appealing!)
michael


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