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Re: cigarette and paxil

Posted by Brandon on February 5, 2000, at 12:56:00

In reply to cigarette and paxil, posted by brian on February 5, 2000, at 11:54:39

Brian,

Nicotine does contain a MAOI but only in the B type. Their are two types of MAOI type A and type B. Type A inhibitors such as Parnate, and Nardil mainly prevent the breakdown of serotonin and norepenephrine that is where the chance of interaction would be greatest. Type B however primarily inhibits the breakdown of dopamine and to some extent norepenephrine. And nicotine does this weakly compared to its other pharmacologic effects. That is why people who smoke on prozac and such dont keel over:) Hope this helps.

Brandon


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poster:Brandon thread:20558
URL: http://www.dr-bob.org/babble/20000128/msgs/20561.html