Posted by michael on January 20, 2000, at 16:16:47
In reply to Re: what the heck is a partial agonist?, posted by Elizabeth on January 20, 2000, at 9:19:12
> My understanding is that a partial agonist is a drug that activates a receptor to less than the maximum extent. I don't know how to express this quantitatively, though. (Where's Adam when we need him! :-) I think that the partial agonists can behave as antagonists at high concentrations.
>
> Buspar is a partial agonist at 5-HT1a receptors and, I believe, a full antagonist at D2 receptors.Could someone rephrase the last sentance above, without using the words agonins & antagonist? What's the net effect on the serotonin & dopamine levels/availability?
michael
poster:michael
thread:19073
URL: http://www.dr-bob.org/babble/20000112/msgs/19280.html