Posted by saint james on October 5, 1999, at 23:09:51
In reply to Re: SAMe -- James there, that would be saint..., posted by dj on October 1, 1999, at 20:00:48
> SJ,
>
> I believe you made the exact same statement in another post someplace here. On what do you base your convictions/conclusion?
>
James here...I made this issue confused by mixing SAMe and precusors in the same post, SAMe dose not fall into the percursor/feedback issue. Let me sort this out...
Taking in additional precursors ( generally the 8 essencial aminos, L-trip is one) to make more brain chems, dosn't work because of the feed back loop and becuase depression is not caused by a lack of chems, but what the body does with those chems. It is by down regulation and slowing reuptake of NT's that AD's work.
I tried SAMe many years ago ( I have had considerable experience with "smart drugs")
and found it to make some difference. However depression, if not treated completely, is a chronic, progressive process, that always gets worse, happens more often, and becomes more resistant. Being 40-50% better is not enough, you need to be completly well, or the depression will return and get worse. Traditional AD's treat my depression completely.... i am happy 360 days a year since 1985. From my reading and experience with SAMe, percursors, and others I find them to not be robust AD's and are better adjuncts to AD's. Depression is big business, and I fear people will take these OTC products will limp along "less than well" and be happy with that, not realizing the long term issues of undertreating depression. A doctor needs to be the one deciding, with the patient, if any treatment is working, and if complete remission has happened. Herbs and others are great for little problems, but I am not in favor of treating depression w/o a doctors consult.
poster:saint james
thread:12407
URL: http://www.dr-bob.org/babble/19991001/msgs/12610.html