Posted by Adam on October 1, 1999, at 12:10:49
In reply to Selegiline for depression?, posted by Brandon on May 10, 1999, at 23:07:11
Well, today is the first day that I begin the open label portion of the transdermal selegiline
study. I am now guranteed a 20mg/patch dose of selegiline HCl for six months.Up to this point I have been dubious enough about selegiline's efficacy for me to wonder if in fact
I might be on the placebo, or, at least, I was in the low dose group (10mg patch). We'll see how
things go. I am noticing no side effects at all from a 20mg/patch dose. From the literature I have
read, in rats selegiline delivered through the skin reaches much higher blood level mg/kg than when
delivered orally, so even 20mg/patch ought to be a whopping effective dose of selegiline. I am
quite suprised by the absence of adverst effects, though I have been told this is not uncommon. I
guess I was hoping I might notice something (which would let me know unequivocably that I was on
a placebo all along and there's still hope I'll get a robust response to selegiline), but such is
not the case.> Has anyone heard of selegiline for depression. I have heard that it can be helpful.
poster:Adam
thread:5905
URL: http://www.dr-bob.org/babble/19991001/msgs/12397.html