Posted by Nick on April 10, 1999, at 13:37:54
In reply to Re: Dysthymia/Treatment Resistant Depressions, posted by Elaine on April 9, 1999, at 23:16:52
> I have been dx'd bipolar (NOS) but also have dysthymia. Do you know if this type of medication is supposed to be effective for depression in bipolars, particularly acute depressions?
I don't know of anything yet BUT both risperidone and olanzapine have mood lifting properties and can also be useful for the treatment of mania/hypomania. However, they have a different mechanism of action to amisulpride (D2, D3 blocker, although potentiates DA transmission at low dose) Risperidone MAY be undergoing trials in bipolar disorder as a single therapeutic agent. I would have thought that amisulpiride might be a reasonable experiment, although at low dose with potentiation of DA transmission there is a risk (theoretically) of precipitating mania.
poster:Nick
thread:4588
URL: http://www.dr-bob.org/babble/19990501/msgs/4650.html