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Re: Other combinations

Posted by Nick on March 24, 1999, at 15:10:40

In reply to Re: Insomnia, Vivid dreams, reboxetine & efexor, posted by Elizabeth on March 24, 1999, at 14:17:23


> They're not used so much here anymore, either, but recently the combination of SSRI (usually Prozac) + low-dose desipramine has gotten - uh, trendy :-) - if the SSRI by itself does not help enough.

Interesting - the main metabolite of lofepramine is desipramine; desipramine is no longer in use here because of cardiotoxicity, yet lofepramine is pretty safe in overdose. Go figure. Other 'heroic' combinations include nefazadone + venlafaxine (I think Steven Stahl uses this one) + the old favourites of TCA + MAOI (ouch). Some evidence for buspirone + SSRIs & pindolol + SSRIs. Its a complicated world.

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poster:Nick thread:3603
URL: http://www.dr-bob.org/babble/19990301/msgs/3960.html