Posted by Elizabeth on March 10, 1999, at 21:58:50
In reply to Re: Atypical depression options, posted by Jim on March 10, 1999, at 8:51:10
> As for your naltrexone comments (which basically answer my question in the other thread about buprenorphine!), you're right that it's mostly been used adjunctively to jumpstart SSRIs or the like. I'm not convinced it causes dyphoria across the board however--several recent reports on alcoholism and various "impulse disorders" seem to suggest that it can help with depressive symptoms in certain patients even when used alone, but the jury's still out on this one.
It's also what I heard from a psychopharm researcher who has quite a bit of experience using opioids (both the mixed agonist/antagonists and Revia) for non-substance-related psych disorders. Certainly it's not an absolute - some people won't feel crappy on it - but I get the impression that (1) a lot do, and (2) people who've studied it get the same impressino.
I sort of agree with you about interpersonal sensitivity (I think it tends to be broader than just "rejecton sensitivity BTW) being the flip side of "reactive mood." Howeer, the way they define reactive mood, it only refers to the ability to be influenced positively by one's environment. (As an aside, I think that most people, including those with so-called typical or melancholic depression, retain the ability to feel *worse* due to things in the environment while depressed.)
-elizabeth
poster:Elizabeth
thread:3449
URL: http://www.dr-bob.org/babble/19990301/msgs/3587.html