Posted by Elizabeth on January 19, 1999, at 1:05:49
In reply to Re: Meds, posted by Toby on January 11, 1999, at 10:33:11
> The pharmacology of Effexor is as I described. At low doses it blocks only serotonin reuptake. At medium to high doses it blocks both serotonin and norepinephrine and at very high doses it blocks dopamine as well as the other two. Stephen Stahl, MD PHD has written some very clear and concise articles and texts on the pharmacology of antidepressants and antipsychotics, if you are looking for a good reference.
Okay, so it *doesn't* act as an MAOI. That's what I thought.
I'm not so clear that the means whereby neurotransmitter concentrations are increased is irrelevant. There seem to be quite a few differences between MAOIs and mixed reuptake inhibitors, even though they would seem to have the same effects, if you just look at which neurotransmitter levels are affected.
Also, I think that saying that Effexor "acts like an MAOI" at high doses may have confused/alarmed some people (because of all the food and drug interactions associated with MAOIs).
poster:Elizabeth
thread:2088
URL: http://www.dr-bob.org/babble/19990101/msgs/2524.html