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Re: Pindolol

Posted by Elizabeth on January 18, 1999, at 8:28:06

In reply to Re: Pindolol, posted by Susan on January 11, 1999, at 18:50:31

> I've heard Pindolol having a sedating effect but also causing insomnia, but my Phsc Dr says this should not happen.

Beta blockers (propranolol, pindolol, etc.) can cause sleep disturbances, yes, even thought they also tend to make you feel zonked. Some people also have nightmares. Might consider taking a lower dose, if possible.

I've never taken pindolol, although I have used propranolol and atenolol intermittently for tremor and tachycardia. Didn't notice sleep problems, did feel a little tired. (10mg of propranolol, 50 of atenolol.)

Pindolol is a serotonin receptor (5-HT1a) antagonist (another such drug is BuSpar), which might account for its antianxiety effects, as well as its usefulness in boosting antidepressants. I think that Dr. Bob's page has a link to a BTP article on pindolol augmentation of antidepressants; there's also a Psychopharmacology Tips page on this subject (http://www.dr-bob.org/tips/).


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URL: http://www.dr-bob.org/babble/19990101/msgs/2488.html