Posted by Toby on December 10, 1998, at 16:15:10
In reply to Re: Thanks Toby, I've still got a few more ???'s , posted by Michael Schell on December 7, 1998, at 12:30:40
Zyprexa actually causes a round-about boosting of serotonin (but in ways I can't begin to explain in any way that makes sense, what with me being a clinician and not a researcher) and that's the effects we're looking for, not necessarily a specific dopamine effect. The dose to start with is usually 2.5 but then gradually increasing up to 20 mg or so. The weight gain varies among different people between none and 5-10 pounds although I have heard tell of 15-20 pounds (just never had any of my patients gain that much).
I like pindolol best because it too has a serotonin boosting effect and I don't see much in the way of drastic drops in blood pressure. I have seen only one good report on Buspar augmentation for OCD but some clinicians say it does well. If you have been on it over 6 months with no benefit, a change to something else for the anxiety may be in order.
The stimulants don't appear to reduce serontonin in the long run. Otherwise you'd have a lot of ADD kids running around without any serotonin.
poster:Toby
thread:1434
URL: http://www.dr-bob.org/babble/19981201/msgs/1529.html