Posted by Toby on December 1, 1998, at 15:47:04
In reply to Remeron for OCD (includes response to Toby), posted by Matt on December 1, 1998, at 3:27:15
Indeed you are correct that Serzone does little for OCD... by itself. It is helpful sometimes in treatment resistent OCD when added to an SSRI. It has something to do with a balancing act between the different subtypes of serotonin receptors (of which there are many). Treatment for OCD relies on boosting serotonin far more than norepinephine and generally the doses of SSRI's are much higher for OCD than for depression. Since the higher the dose of Remeron the more norepinephine it boosts, I don't know if that would affect its ability to help OCD; the balancing act may be important here too. So it remains to be seen if Remeron will be helpful for OCD but I still think it may be helpful as an augmenting agent, even if not all by itself, like Serzone.
Thoughts from other docs?
poster:Toby
thread:1409
URL: http://www.dr-bob.org/babble/19981201/msgs/1416.html