Psycho-Babble Medication Thread 1120470

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FDA approves Axsome (dextromethorphan + bupropion)

Posted by SLS on August 24, 2022, at 11:11:16

Hi, All.

The FDA approved Axsome (dextromethorphan + bupropion) on August 19.


"On 19 August, the US Food and Drug Administration (FDA ) approved Axsome Therapeutics (US) Auvelity (dextromethorphan + bupropion) for the treatment of major depressive disorder (MDD) in adults. Auvelity is the first orally administered product with a novel mechanism of action (MOA) to enter the MDD market in more than 60 years. The dextromethorphan component targets the N-methyl D-aspartate (NMDA) receptor and the sigma-1 receptor in the brain, while the bupropion component acts to increase levels of dextromethorphan in the blood."

"The drug, Auvelity, is a new class of treatment that reduces the symptoms of depression as early as one week, giving it a potential edge over older antidepressants, which can take up to six weeks to show effect."

https://www.clinicaltrialsarena.com/comment/fda-axsome-therapeutics/


- Scott

 

Name correction:

Posted by SLS on August 24, 2022, at 11:15:13

In reply to FDA approves Axsome (dextromethorphan + bupropion), posted by SLS on August 24, 2022, at 11:11:16

Correction:

The drug name is Auvelity (dextromethorphan + bupropion).

The drug company is Axsome Therapeutics.


- Scott

 

Re: FDA approves Axsome (dextromethorphan + bupropion)

Posted by undopaminergic on August 25, 2022, at 12:16:45

In reply to FDA approves Axsome (dextromethorphan + bupropion), posted by SLS on August 24, 2022, at 11:11:16

> ... The dextromethorphan component targets the N-methyl D-aspartate (NMDA) receptor and the sigma-1 receptor in the brain, while the bupropion component acts to increase levels of dextromethorphan in the blood."
>
> "The drug, Auvelity, ...

This is the one I reported a few days ago. Thanks for the added information (above).

-undopaminergic


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