Shown: posts 1 to 21 of 21. This is the beginning of the thread.
Posted by Hugh on March 17, 2022, at 12:08:29
In 2020, Russell Hinton, a private psychiatrist, described how he treated the first patient. This was a woman who had tried more than a dozen different medications for her bipolar. She had been hospitalized ten times, had gained considerable weight and judged she had no quality of life.
After a poo transplant from her husband, she became symptom-free over the next five years, lost 33 kilograms [72 pounds], required no medication and her career bloomed.
Gordon Parker and colleagues at the University of New South Wales reported their results with the second patient last month. This was a young man who developed bipolar as a teenager, had tried numerous medications and became progressively intolerant of their side effects.
After a poo transplant, he was able to progressively cease all medications over the next year, and had virtually no mood swings. He also noted an improvement in his anxiety and ADHD (attention deficit hyperactivity disorder).
Abnormal gut microbiomes have been linked to bipolar, depression and schizophrenia.
When poo from depressed humans is given to rats, they appear to develop a rat version of depression. Likewise, when mice are given poo from someone with schizophrenia, they develop a mouse version of schizophrenia.
Complete article:
https://medicalxpress.com/news/2022-03-poo-dose-day-bipolar-mental.html
Posted by Lamdage22 on March 17, 2022, at 15:36:15
In reply to Fecal transplant in 2 bipolar patients, posted by Hugh on March 17, 2022, at 12:08:29
And abnormal gut microbiomes are linked to antibiotics... I just wonder if I could get an infection or an autoimmune issue with the transplant. I have been considering it. So what now? Ask my brother for some of his poo? Aint gonna happen :)
Posted by Lamdage22 on March 17, 2022, at 15:41:51
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 17, 2022, at 15:36:15
BTW abnormal gut microbiomes are passed along from mother to child. You get most of your microbiome from your mother.
Posted by Hugh on March 18, 2022, at 12:13:45
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 17, 2022, at 15:36:15
At medical facilities that perform fecal transplants, they screen the donors for disease.
Posted by linkadge on March 18, 2022, at 19:34:41
In reply to Re: Fecal transplant in 2 bipolar patients » Lamdage22, posted by Hugh on March 18, 2022, at 12:13:45
Interesting. I have heard of some success with fecal transplants in autism. I wonder what the success rate would be for such treatments in bipolar. I am a bit skeptical that a fecal transplant (or probiotics) would eliminate the need for mood stabilizers entirely for most patients.
Also, diet, exercise, stress and medications can also alter the microbiome. Things like dirt exposure and other environmental factors too can have an impact. For example, some studies showed that rTMS can alter the microbiome (that is, the brain influencing gut bacteria). So, it's probably bidirectional.
Linkadge
Posted by PeterMartin on March 19, 2022, at 0:05:18
In reply to Re: Fecal transplant in 2 bipolar patients, posted by linkadge on March 18, 2022, at 19:34:41
I'm very excited about the research into fecal transplants - I hope they're demonstrated to be safe, and can become an option. I've always thought of them as most likely to be beneficial for obesity but I do believe in the concept......hope to see more in the near future.
Posted by Lamdage22 on March 19, 2022, at 2:18:46
In reply to Re: Fecal transplant in 2 bipolar patients » Lamdage22, posted by Hugh on March 18, 2022, at 12:13:45
> At medical facilities that perform fecal transplants, they screen the donors for disease.
I hope they do so with diligence. I would like to do a transplant if the risk of infection or autoimmune is low. I'd like to know about the donor tough. There is people considered healthy that are not so healthy in my eyes.
Posted by Jay2112 on March 19, 2022, at 11:00:03
In reply to Re: Fecal transplant in 2 bipolar patients, posted by linkadge on March 18, 2022, at 19:34:41
> Interesting. I have heard of some success with fecal transplants in autism. I wonder what the success rate would be for such treatments in bipolar. I am a bit skeptical that a fecal transplant (or probiotics) would eliminate the need for mood stabilizers entirely for most patients.
>
> Also, diet, exercise, stress and medications can also alter the microbiome. Things like dirt exposure and other environmental factors too can have an impact. For example, some studies showed that rTMS can alter the microbiome (that is, the brain influencing gut bacteria). So, it's probably bidirectional.
>
> Linkadge
>
>There are very specific strains of probiotics, in certain balances, that seem to be hard to come across, that work quite well in autism. I know of some that treat autism quite well, but I can't recall the name of the one strain. You can find some of the user info on reddit. My pdoc seems to think I possibly have some type of variation of an autistic disorder, as he specializes in the area. The proven treatments, Risperdal and nefadozone, have been the most effective meds for me, over 30 or so years. I have the typical very severe social anxiety, and the 'meltdowns'. This is my 3rd psychiatrist who has made such a diagnosis.
Jay
Posted by Hugh on March 20, 2022, at 15:57:08
In reply to Re: Fecal transplant in 2 bipolar patients » linkadge, posted by Jay2112 on March 19, 2022, at 11:00:03
Prebiotics can significantly improve microbiome health. This prebiotic mixture is composed of chickpea flour, peanut flour, soy flour, green banana flour, sugar, and soybean oil or olive oil.
Posted by Lamdage22 on March 21, 2022, at 5:44:30
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Hugh on March 20, 2022, at 15:57:08
It is counterintuitive to eat sh*t in order to get better.
Posted by Lamdage22 on March 21, 2022, at 5:46:39
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 21, 2022, at 5:44:30
Maybe that is why dogs sniff echothers butts. They wanna make sure the microbiome is ok.
Posted by Lamdage22 on March 21, 2022, at 6:00:11
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 21, 2022, at 5:46:39
Telling people to eat sh*t is actually supportive.
Posted by Hugh on March 22, 2022, at 13:12:42
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 21, 2022, at 6:00:11
> Telling people to eat sh*t is actually supportive.
That's true. Knowing what we now know, it's like saying gesundheit.
Posted by Lamdage22 on March 22, 2022, at 22:00:51
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Hugh on March 20, 2022, at 15:57:08
> Prebiotics can significantly improve microbiome health. This prebiotic mixture is composed of chickpea flour, peanut flour, soy flour, green banana flour, sugar, and soybean oil or olive oil.
>
> https://www.npr.org/sections/goatsandsoda/2019/07/11/740820882/a-mix-of-these-foods-could-restore-healthy-microbes-in-malnourished-kidsWhat do you think about probiotics? Which strains?
Posted by Lamdage22 on March 23, 2022, at 4:23:34
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 21, 2022, at 5:46:39
Is it possible to get character traits from the donor? Good or bad? It seems conceivable to me. That could be a good thing or not.
Posted by Hugh on March 23, 2022, at 14:45:01
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 22, 2022, at 22:00:51
I've tried lots of probiotics. Culturelle is a good one. My favorite is kefir (fermented milk).
> > Prebiotics can significantly improve microbiome health. This prebiotic mixture is composed of chickpea flour, peanut flour, soy flour, green banana flour, sugar, and soybean oil or olive oil.
> >
> > https://www.npr.org/sections/goatsandsoda/2019/07/11/740820882/a-mix-of-these-foods-could-restore-healthy-microbes-in-malnourished-kids
>
> What do you think about probiotics? Which strains?
>
>
Posted by Hugh on March 23, 2022, at 14:48:13
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 23, 2022, at 4:23:34
> Is it possible to get character traits from the donor? Good or bad? It seems conceivable to me. That could be a good thing or not.
Absolutely. You would not want to get a fecal transplant from someone who is depressed, anxious or obese. You would want to get one from the Dalai Lama.
Posted by Lamdage22 on March 24, 2022, at 0:04:06
In reply to Re: Fecal transplant in 2 bipolar patients » Lamdage22, posted by Hugh on March 23, 2022, at 14:48:13
What about people though who get better through therapy? Maybe not only the microbiome influences us but also the other way around? Cause it happens that people get really good with serious therapy.
Posted by Lamdage22 on March 24, 2022, at 13:39:22
In reply to Re: Fecal transplant in 2 bipolar patients » Lamdage22, posted by Hugh on March 22, 2022, at 13:12:42
> > Telling people to eat sh*t is actually supportive.
>
> That's true. Knowing what we now know, it's like saying gesundheit.With this knowledge, we should go out into the world and teach better manners. Some already get it though.
Posted by Jay2112 on March 26, 2022, at 21:18:41
In reply to Re: Fecal transplant in 2 bipolar patients, posted by Lamdage22 on March 21, 2022, at 6:00:11
> Telling people to eat sh*t is actually supportive.
lol....I could see this as a Monty Python episode. :)
Posted by Lamdage22 on April 23, 2022, at 12:49:06
In reply to Re: Fecal transplant in 2 bipolar patients » Lamdage22, posted by Jay2112 on March 26, 2022, at 21:18:41
I am taking probiotics now. I had a stool test which showed low lacto and bifido bacillus levels. Also too many putrefaction flora. I will see how it goes. In my mind any improvement in health also improves mental health. Indirectly at least. They are not seperated from eachother.
This is the end of the thread.
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