Psycho-Babble Medication Thread 1117547

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Microdosing psychedelics for anxiety, depression

Posted by Hugh on November 27, 2021, at 11:42:14

https://globalnews.ca/news/8396650/ubc-psychedelics-mental-health-study/

An international study led by the University of British Columbia's Okanagan campus suggests that repeated, small doses of psychedelic drugs can help treat some mental health issues.

The research published last week found that adults who used regular microdoses of LSD or psilocybin -- also known as magic mushrooms -- showed fewer symptoms of anxiety and depression than those who did not. They also reported greater feelings of well-being.

"There was a clear association between microdosing and fewer symptoms of depression, anxiety and stress, which is important given the high prevalence of these conditions and the substantial suffering they cause," said lead author and UBC Okanagan doctoral student Joseph Rootman in a news release.

The study followed more than 8,500 people from 75 countries using an anonymous self-reporting system. About half of were microdosing.

The most commonly-used psychedelic in the study was magic mushrooms, but participants reported different dosages, frequencies and practices, including stacking -- the combining of psilocybin with non-psychedelic substances, like chocolate and lions mane mushrooms.

According to UBC, the study is the first to systemically examine stacking.

"We have an epidemic of mental health problems, with existing treatments that don't work for everyone," said Dr. Zach Walsh, a psychology professor at UBC Okanagan.

"We need to follow the lead of patients who are taking these initiatives to improve their well-being and reduce suffering."

The study reported health and wellness were most prominent motivations for participants who were microdosing, and were even more prominent among women who reported mental health concerns.

Its authors say the study highlights the need for additional research into mental health and microdosing, with "rigorous longitudinal" designs.

The study:

https://www.nature.com/articles/s41598-021-01811-4

 

Re: Microdosing psychedelics for anxiety, depression

Posted by PeterMartin on November 27, 2021, at 22:21:36

In reply to Microdosing psychedelics for anxiety, depression, posted by Hugh on November 27, 2021, at 11:42:14

There are good groups on Reddit for anecdotes/tips from people who do this "microdosing" stuff.

I never have, but that seems to be the place w/ the best discussion about it.

 

Re: Microdosing psychedelics for anxiety, depression

Posted by Lamdage22 on December 4, 2021, at 5:55:41

In reply to Re: Microdosing psychedelics for anxiety, depression, posted by PeterMartin on November 27, 2021, at 22:21:36

How far is Psilocybin from FDA approval?

 

Re: Microdosing psychedelics for anxiety, depression Lamdage22

Posted by Hugh on December 7, 2021, at 12:55:00

In reply to Re: Microdosing psychedelics for anxiety, depression, posted by Lamdage22 on December 4, 2021, at 5:55:41

> How far is Psilocybin from FDA approval?

Psilocybin therapy for depression is something you can do right now in Amsterdam.

https://qz.com/1918001/psychedelic-therapy-for-depression-is-on-sale-for-the-first-time/

https://www.synthesisretreat.com/

In the US, Oregon has legalized psilocybin therapy.

 

Re: Microdosing psychedelics for anxiety, depression Hugh

Posted by Jay2112 on December 8, 2021, at 15:50:43

In reply to Re: Microdosing psychedelics for anxiety, depression Lamdage22, posted by Hugh on December 7, 2021, at 12:55:00

> > How far is Psilocybin from FDA approval?
>
> Psilocybin therapy for depression is something you can do right now in Amsterdam.
>
> https://qz.com/1918001/psychedelic-therapy-for-depression-is-on-sale-for-the-first-time/
>
> https://www.synthesisretreat.com/
>
> In the US, Oregon has legalized psilocybin therapy.
>
>

Hi Hugh:

Would psilocybin use be problematic for someone with bipolar disorder, like me? I do have a source, but am scared, as I also have had a couple of psychotic incidents.

Thanks,
Jay

 

Re: Microdosing psychedelics for anxiety, depression Jay2112

Posted by Hugh on December 10, 2021, at 10:48:30

In reply to Re: Microdosing psychedelics for anxiety, depression Hugh, posted by Jay2112 on December 8, 2021, at 15:50:43

> Hi Hugh:
>
> Would psilocybin use be problematic for someone with bipolar disorder, like me? I do have a source, but am scared, as I also have had a couple of psychotic incidents.
>
> Thanks,
> Jay

Hi Jay,

If you decide to try psilocybin, don't be alone when you do it. This site lists therapists who help to guide patients through their psychedelic experience:

https://integration.maps.org/

These two sites deal with psilocybin and bipolar disorder:

https://www.sciencedirect.com/science/article/pii/S2666915321001669

https://www.crestbd.ca/2021/07/05/bipolar-psilocybin-study-poster/

 

Re: Microdosing psychedelics for anxiety, depression Hugh

Posted by SLS on December 13, 2021, at 8:18:51

In reply to Re: Microdosing psychedelics for anxiety, depression Lamdage22, posted by Hugh on December 7, 2021, at 12:55:00

> > How far is Psilocybin from FDA approval?
>
> Psilocybin therapy for depression is something you can do right now in Amsterdam.
>
> https://qz.com/1918001/psychedelic-therapy-for-depression-is-on-sale-for-the-first-time/
>
> https://www.synthesisretreat.com/
>
> In the US, Oregon has legalized psilocybin therapy.


In none of the articles you posted could I find the words "rating" or "score" referencing anxiety or depression. These articles are nothing more than a collection of self-reported reflective anecdotes. Perhaps I missed something. RCTs might one day affirm these anecdotes. But for now, I am being cautious in coming to any conclusions.


- Scott

 

Re: Microdosing psychedelics for anxiety, depression SLS

Posted by Hugh on December 15, 2021, at 12:38:18

In reply to Re: Microdosing psychedelics for anxiety, depression Hugh, posted by SLS on December 13, 2021, at 8:18:51

> In none of the articles you posted could I find the words "rating" or "score" referencing anxiety or depression. These articles are nothing more than a collection of self-reported reflective anecdotes. Perhaps I missed something. RCTs might one day affirm these anecdotes. But for now, I am being cautious in coming to any conclusions.
>
>
> - Scott

ClinicalTrials.gov lists 77 ongoing clinical trials for psilocybin, so we'll know a lot more down the road about their efficacy for depression and anxiety.

I've posted here before about my own experiences with psilocybin. Many years ago, a dose of magic mushrooms lifted me out of a severe, suicidal depression.

 

Re: Microdosing psychedelics for anxiety, depression

Posted by alchemy on December 30, 2021, at 21:04:42

In reply to Re: Microdosing psychedelics for anxiety, depression SLS, posted by Hugh on December 15, 2021, at 12:38:18

I tried microdosing psilocybin and it made me worse. I was so hopeful. It took a while to recover. Other reddit posters have had negative experiences, although most are very positive.

 

Re: Microdosing psychedelics for anxiety, depression

Posted by Englishman006! on March 6, 2022, at 13:20:46

In reply to Re: Microdosing psychedelics for anxiety, depression, posted by alchemy on December 30, 2021, at 21:04:42

> I tried microdosing psilocybin and it made me worse. I was so hopeful. It took a while to recover. Other reddit posters have had negative experiences, although most are very positive.

It made me worse too, more anxious and depressed!


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