Psycho-Babble Medication Thread 1117067

Shown: posts 1 to 8 of 8. This is the beginning of the thread.

 

Glutamine

Posted by Lamdage22 on September 24, 2021, at 15:15:47

Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/

What does science say?

 

Re: Glutamine

Posted by Jay2112 on September 24, 2021, at 18:37:03

In reply to Glutamine, posted by Lamdage22 on September 24, 2021, at 15:15:47

> Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/
>
> What does science say?

Hmmm..well, I am an Adult Educator, no real hard science. But, I think you should be careful with Glutamate. Glutamate, or l-glutamate, are precursor's to NMDA, and mood stabilizers and other's are NMDA antagonists.

Just IMHO, YMMV, etc..
Jay

 

Re: Glutamine

Posted by sigismund on September 24, 2021, at 21:38:49

In reply to Re: Glutamine, posted by Jay2112 on September 24, 2021, at 18:37:03

Sometimes it converts into glutamate, sometimes into GABA. Does that depend on mineral cofactors?

 

Re: Glutamine

Posted by Lamdage22 on September 25, 2021, at 0:27:37

In reply to Re: Glutamine, posted by sigismund on September 24, 2021, at 21:38:49

Ok. Isnt there a glutamate hypofunction hypothesis of schizophrenia? My issues have a tendency towards that diagnosis. I do take Neuroleptics.

 

Re: Glutamine Lamdage22

Posted by undopaminergic on September 25, 2021, at 0:32:05

In reply to Re: Glutamine, posted by Lamdage22 on September 25, 2021, at 0:27:37

> Ok. Isnt there a glutamate hypofunction hypothesis of schizophrenia?

Yes, it is the most modern hypothesis.

-undopaminergic

 

Re: Glutamine

Posted by undopaminergic on September 25, 2021, at 0:34:35

In reply to Re: Glutamine, posted by Jay2112 on September 24, 2021, at 18:37:03

> > Im taking a glutamine enriched protein powder and feeling pretty decent. https://pubmed.ncbi.nlm.nih.gov/30266598/
> >
> > What does science say?
>
> Hmmm..well, I am an Adult Educator, no real hard science. But, I think you should be careful with Glutamate. Glutamate, or l-glutamate, are precursor's to NMDA, and mood stabilizers and other's are NMDA antagonists.
>

Glutamine is a precursor to glutamate and GABA. NMDA does not occur naturally in the body.

Memantine is a NMDA-glutamate antagonist, and can cause mania.

-undopaminergic

 

Re: Glutamine

Posted by sigismund on September 25, 2021, at 1:51:48

In reply to Re: Glutamine, posted by undopaminergic on September 25, 2021, at 0:34:35

Excitotoxicity used to be discussed more. That's to do with this?

 

Re: Glutamine

Posted by undopaminergic on September 25, 2021, at 5:10:12

In reply to Re: Glutamine, posted by sigismund on September 25, 2021, at 1:51:48

> Excitotoxicity used to be discussed more. That's to do with this?

A certain degree of excess agonism at glutamate receptors is excitotoxic.

I said NMDA does not occur naturally in the body, but the Wikipedia article claims it functions as a neurotransmitter:
https://en.wikipedia.org/wiki/N-Methyl-D-aspartic_acid

-undopaminergic


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