Psycho-Babble Medication Thread 208518

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*Very* slow titration of Paxil to avoid s/efx

Posted by Ame Sans Vie on March 12, 2003, at 18:55:45

I know I'm really reaching here, but I will admit Paxil has been moderately helpful in the past for my SP/agoraphobia/panic/god-knows-what-else. The side effects were just killer though. I mean, I could actually handle the mood-flattening/apathy, but the mental clouding and sexual side effects were too much to bear. But even still, I'm pretty much stuck at this point. My new doctor has mentioned Xyrem and buprenorphine as future possibilities, but will only consider them after more conservative approaches are tried. So what I'm wondering is, would a very slow titration (over the course of six months or so, using the Paxil liquid suspension, up to about 60mg) stand any chance of reducing the occurrence of adverse effects? Would it even be worth trying? Paxil never offered anywhere near complete relief of the symptoms. But maybe in combination with 16mg clonazepam it'll be enough to get by on.

 

16 mg Klonopin? You're joking, right? (nm) Ame Sans Vie

Posted by Jack Smith on March 13, 2003, at 12:49:38

In reply to *Very* slow titration of Paxil to avoid s/efx, posted by Ame Sans Vie on March 12, 2003, at 18:55:45

 

Re: 16 mg Klonopin? You're joking, right? Jack Smith

Posted by Ame Sans Vie on March 14, 2003, at 6:24:00

In reply to 16 mg Klonopin? You're joking, right? (nm) Ame Sans Vie, posted by Jack Smith on March 13, 2003, at 12:49:38

Not at all... I just don't respond to anything less, and even with this dose it takes at least two weeks for me to start feeling any effect. I figure this high dose of clonazepam is better than the next option we're trying anyway, which is buprenorphine. I don't have anything against trying it, but I'm quite a bit concerned about developing tolerance. Tolerance to clonazepam has never been an issue for me.

 

Re: 16 mg Klonopin? You're joking, right?

Posted by utopizen on March 14, 2003, at 11:22:31

In reply to Re: 16 mg Klonopin? You're joking, right? Jack Smith, posted by Ame Sans Vie on March 14, 2003, at 6:24:00

> Not at all... I just don't respond to anything less, and even with this dose it takes at least two weeks for me to start feeling any effect. I figure this high dose of clonazepam is better than the next option we're trying anyway, which is buprenorphine. I don't have anything against trying it, but I'm quite a bit concerned about developing tolerance. Tolerance to clonazepam has never been an issue for me.

I remember, before maturing about my meds, I took 4mg of Klonopin for the first time when I got it as a prn, never had it before. It was like my hand greedily grabbed it like a robot and shoved it down my mouth (girls coming over in 20 minutes, I was anxious). Well, sure enough, 1/2 later, I was nodding my head down as if I could no longer suppose it upright and slowly said good-bye to my friends as they left. Don't remember anything for the next 12 hrs.

 

Re: 16 mg Klonopin? You're joking, right? utopizen

Posted by Ame Sans Vie on March 14, 2003, at 12:10:26

In reply to Re: 16 mg Klonopin? You're joking, right?, posted by utopizen on March 14, 2003, at 11:22:31

>I remember, before maturing about my meds, I took 4mg of Klonopin for the first time when I got it as a prn, never had it before. It was like my hand greedily grabbed it like a robot and shoved it down my mouth (girls coming over in 20 minutes, I was anxious). Well, sure enough, 1/2 later, I was nodding my head down as if I could no longer suppose it upright and slowly said good-bye to my friends as they left. Don't remember anything for the next 12 hrs.

I suppose I just got lucky, concerning drowsiness from Klonopin, or any med for that matter. Which can be kind of a double-edged sword. I have yet to find *anything* prescription or otherwise that can help me sleep if I ever need it. Luckily that's very rare for me as I tend to fall asleep easily and actually oversleep as it is.

 

Re: Tolerance

Posted by exbenzouser on March 17, 2003, at 15:48:24

In reply to Re: 16 mg Klonopin? You're joking, right? Jack Smith, posted by Ame Sans Vie on March 14, 2003, at 6:24:00

> Not at all... I just don't respond to anything less, and even with this dose it takes at least two weeks for me to start feeling any effect. I figure this high dose of clonazepam is better than the next option we're trying anyway, which is buprenorphine. I don't have anything against trying it, but I'm quite a bit concerned about developing tolerance. Tolerance to clonazepam has never been an issue for me.

You have to take 16mg and you don't think you have a problem with tolerance?

 

Re: Tolerance

Posted by Ame Sans Vie on March 17, 2003, at 16:42:06

In reply to Re: Tolerance, posted by exbenzouser on March 17, 2003, at 15:48:24

Well, I haven't *developed* tolerance if that's what you mean. I've always needed this high a dose. So I suppose I have a naturally high tolerance, or more likely an extremely severe case of agoraphobia/social anxiety, but what I was trying to get across was that growing tolerant to it has never been an issue.


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