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Re: clomipramine insomnia - does it ever go away? undopaminergic

Posted by SLS on January 29, 2023, at 10:10:29

In reply to Re: clomipramine insomnia - does it ever go away? SLS, posted by undopaminergic on January 29, 2023, at 9:54:29

Hi.

> > I insist that lithium displays a similar clinical trait. For me, 300 mg/day is magic. At 450 mg/day, I very quickly relapse. Lithium has been reported to have a biphasic effect on glutamate release. You commented on this, noting that this bimodal pharmacological property displays a dosage-response curve regarding glutamate release, but can yield conflicting clinical results depending on the study being examined.


> So there is some other study (beyond the one I cited) pertaining to this effect?

Yes - and it was a clinical study of how people reacted to low-dosage versus high-doage lithium. I have been racking my brain trying to locate it again.


> > > > 3. Herbal teas. Valerian is mentioned often. Chamomile, lemon grass, and eleuthero are others with reputations as being sleep-aids.


> > > Eleutherococcus is also called Siberian Ginseng.

> > I wish I had your memory.


> I think my memory is at its best when it comes to drugs. Contrast that with mathematics: often I have to determine the result of 3+4 by counting "5, 6, 7".


I know this arithmetic deficit well.


> > I am still having trouble with mine. My guess is that the impairment of short-term memory associated with depression is one of the last things to resolve. I had a few bilateral ECT treatments in the 1990s, so this must be taken into consideration. However, I doubt that there are any residual memory deficits produced by ECT for me. We'll see.


> What memory performance is considered "normal" or "good", and how is it measured? There are some answers to that, I'm sure, and it is a science in itself, but the point I'm hinting at is that almost everyone seems to think their memory isn't good enough.


I agree. Also, as people age, short-term memory deteriorates.


> > > I got angry from Valerian. It was very unusual in how it started and in its qualities. But it has only happened once.


> > I hate that there are so many differences in the way people respond to a given treatment. Trying to generalize and predict one's reactions to specific drugs is a fool's errand. It is frustrating and makes me feel impotent. We are all trying to help each other in the face of inconsistency and paradox. Dammit.


> Yes.
>
> -undopaminergic


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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