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Re: Trimipramine SLS

Posted by SLS on December 17, 2022, at 19:54:37

In reply to Re: Trimipramine Jay2112, posted by SLS on December 17, 2022, at 19:40:49

Alterations of REM sleep in depression is one of the oldest observations in modern psychiatry.

Normal latency of REM sleep is no shorter than 90 minutes.

The latency of REM sleep in depression is no longer than 60 minutes.

If I recall properly, sleep stage cycles in depression are shorter, too.

MAOIs completely abolish REM sleep. The abrupt discontinuation of a MAOI produces REM rebound. When this occurs, dreams can become extremely vivid. You can also end up being caught between dreaming and wakefullness. You can have your eyes open and see your surroundings, but you can't move. This is sleep paralysis.

One thing that I found very disturbing is that over the years, MAOIs have lost their ability to suppress dreaming for me. This is another demonstration that going on and off an antidepressant can make one resistant to its effects in the future.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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