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Re: Antibiotic greatly enhances efficacy of TMS

Posted by Hugh on November 2, 2022, at 10:28:59

In reply to Antibiotic greatly enhances efficacy of TMS, posted by Hugh on November 1, 2022, at 17:19:52

Drug: D-cycloserine
Daily oral D-cycloserine 100mg during the blinded phase (10 days).
Other Name: Seromycin

Device: Transcranial Magnetic Stimulator
Repetitive Transcranial magnetic stimulation (rTMS) will be delivered using a MagPro X100 device with B70 coil and the intermittent theta burst (iTBS) protocol to the left dorsolateral prefrontal cortex. Participants will receive daily treatments (Monday-Friday) over four weeks.

Participants will orally ingest a capsule containing 100mg of the antibiotic d-cycloserine daily (Monday-Friday) for the first 2 weeks of rTMS treatment (10 sessions), followed by 2 weeks of rTMS without adjunctive medication.




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