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Re: MAOI vs SSRI undopaminergic

Posted by SLS on October 28, 2022, at 8:54:14

In reply to Re: MAOI vs SSRI, posted by undopaminergic on October 28, 2022, at 7:43:17

> > > >
> > > > When will you be trying it?
> > > >
> > >
> > > The memantine? I already did. It was a great remedy for depression, but it produced a manic condition that led me to impulsively take a massive overdose of it, which ended in intensive care followed by psychiatric hospitalisation. I don't think I would feel safe taking it again without someone to monitor me.
> > >
> > > -undopaminergic
> > >
> >
> > I was asking about clorgyline.
> >
>
> Oh, well, that is currently not an alternative. There are other MAOIs to try first, especially tranylcypromine, which I imagine I might also have to acquire from a chemical supplier.
>
> > What if you took an anti-manic along with the memantine?
> >
>
> That might be worth trying.
>
> -undopaminergic


If Zyprexa (olanzapine) has had any beneficial effect for depression when added, regardless of the amount of time that it provided benefit, this might be an indicator that adding the right atypical antipsychotic might act as a synergist to memantine in treating your depression and also prevent mania. Since weight-gain is often a side effect of Zyprexa, finding another AP might solve that problem. Saphris (asenapine) and Latuda (lurasidone) come to mind. I don't know enough about Fanapt (iloperidone), but I would search the Internet for information.

The other anti-manic strategy is to use anticonvulsants. Trileptal (oxcarbazepine), Depakote (valproate), topiramate (Topamax) are worth looking into. They sometimes demonstrate antidepressant effects when used as an adjunct to antidepressants.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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