Psycho-Babble Medication | about biological treatments | Framed
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Posted by undopaminergic on October 23, 2022, at 10:01:11

In reply to MAOI vs SSRI, posted by linkadge on October 22, 2022, at 17:39:33

> I don't think there are any head to head trials comparing the use of these two classes for first episode depression but...
> I wonder...
> If you took 1000 first time depressed patients and randomly prescribed either parnate or escitalopram, I wonder which med would produce a higher response / remission rate.
> MAOIs are currently reserved as a third line treatment, but I just wonder what the repsonse would be if they were given as a first line treatment.
> Linkadge

I'm inclined to think Parnate would win, but I agree it would be interesting to put it to test. I recall something about TCAs being better for "typical" depression and MAOIs for "atypical", but I'm not sure the effects of TCAs generalise fully to SSRIs.





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