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Responsive ) Refractory ) Responsive ) Remission undopaminergic

Posted by SLS on September 28, 2022, at 11:18:06

In reply to Re: Buspar vivid/terrible nightmares? SLS? SLS, posted by undopaminergic on September 28, 2022, at 7:54:46

Hi.

> > I have combined Parnate 120 mg/day with methylphenidate and also with amphetamine. On top of that, came T4 and desipramine. It was of little value if remission was to be my goal.


> What was the problem with the combination? Did it not elevate your mood enough, or did it have adverse effects?


In 1987, after 5 years of treatment failures, a doctor put me on a combination of Parnate and desipramine. It was harsh at first, but it eventually brought me close to remission. Functionally, I was very much improved. However, anhedonia remained less improved. I was quite happy with that state of affairs. After 6 months of remission, a delusional mania emerged for the first time as an adverse effect of drug treatment. The doctor discontinued both antidepressants, and I relapsed within 2 months. My doctor had no intentions of giving me a MAOI + TCA combination ever again - which was a monumental mistake. In 1990, I became psychotically manic after *discontinuing* Nardil. I was still responsive to it, though. I entered a psychiatric clinic as an inpatient. They treated me with Thorazine and then Haldol, after which I became absolutely refractory to all treatments. Taking clorgyline, a *specific* and irreversible MAOI was powerful enough to break through the wall of non-response. I became responsive to drugs again, but it would take another 20 years to find the right treatment for me.

I am now close to being in full remission.

Current treatment regime - :

Nardil - 90 mg/day
Nortriptyline - 150 mg/day
Lamotrigine - 300 mg/day
Lithium - 300 mg/day


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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poster:SLS thread:1120765
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