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Re: remission ))

Posted by SLS on September 23, 2022, at 8:14:05

In reply to Re: remission )) SLS, posted by Jay2112 on September 22, 2022, at 21:08:49

> Greets Scott!
>
> > Hi, Jay.
> >
> > > Hope you are doing well,
> > > Jay :)
> >
> > I am still very much improved. You are kind to ask.
> >
> > I had to raise my dosage of nortriptyline from 100 mg/day to 150 mg/day. It should make a big difference. It already is. 100% remission is keeping my eyes on the prize.
> >
> > Nardil 90 mg/day
> > Nortriptyline 150 mg/day
> > Lamictal 300 mg/day
> > Lithium 300 mg/day
> >
> >
> > - Scott
>
> I am very glad you are doing well, as I know how long it took you to find your 'mix'. Each of us...genetic blends...with uncertain ends...that's a song, I think..lol. I have found nortriptyline to be both energizing (likely it's norepinephrine effect) and sedating (anticholinergic effects). But, glad it is working!
>
> I have come down on Effexor, from 150 to 75mg's, and after 3 weeks, I don't know why the heck I didn't do it sooner! But, I have added 10mg of Trintellix, and wow, after a month, with these 2 changes, I have become the more relaxed guy I *thought* I was...but the damn Effexor, at higher doses, was way, way too stimulating!! Trintellix apparently has some type of small effect on the cholinergic system, and I don't think it is anticholinergic. Maybe, a small bump up of choline transmission, with all my anticholinergics, is a good thing! We will see.

That is so rewarding to read. I hope you continue move forward with your recovery (biological, psychological, occupational, and vocational).

Trintellix is an unusual antidepressant. It binds to a surprising number of different receptor subtypes. This includes the blocking of the serotonin 5-HT7 receptor, one that has been the target of much study recently in the treatment of depression.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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poster:SLS thread:1120713
URL: http://www.dr-bob.org/babble/20220917/msgs/1120777.html