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Re: Hepatitis C drugs may help PTSD Jay2112

Posted by SLS on August 24, 2022, at 21:08:10

In reply to Re: Hepatitis C drugs may help PTSD, posted by Jay2112 on August 24, 2022, at 20:40:04

> For some, Prazosin is ineffective. (Myself included) It did nothing for my nightmares, and made me feel like total sh*t during the day. Clonidine, and one of it's off-shoots I can't recall the name of, combined with propranolol, has been a saviour to me.Perfect combo. I have a very high hart-rate, and these work well to keep me smooth throughout the day. I was diagnosed with PTSD about 7 years ago. I lost a child and partner/wife in a car accident about 24 years ago, but it took that long for me to get decent services and help.
> This combo extinguishes nightmares, as well as intrusive thoughts/flashbacks and severe anxiety in the daytime.
>
> Jay
>


Reports like yours are invaluable, Jay.


Clonidine makes sense. It is a presynaptic NE alpha-2 agonist. It probably dampens the fight-or-flight response. However, clonidine is frequently depressogenic, even with people who never had a depressive episode before.

Of the two drugs, which one helps with the nightmares?


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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