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Re: Would it be wise not to take GABAergics for sleep? Christ_empowered

Posted by SLS on August 22, 2022, at 18:00:03

In reply to Re: Would it be wise not to take GABAergics for sleep?, posted by Christ_empowered on August 22, 2022, at 17:03:17

> an occasional ativan for agitation or restoril for sleep is not ideal, but...effective, usually. and yet...
>
> longer term use creates problems for a lot of people. so, there's that. :-(
>
> never did well with z-hypnotics, personally. extra ativan or klonopin, yes. restoril, yes. but not so much ambien or sonata.


Unlike benzodiazepines, which bind to all GABA-A receptors, the Z- drugs are very selective for the α1-GABA-A receptor subtype. This receptor is most responsible for the hypnotic (sleep-inducing) properties of both the non-selective benzodiazepines and the selective Z- drugs. I took zolpidem (Ambien) for over a year. I was able to stop taking it abruptly without suffering the withdrawal syndrome associated with benzodiazepine discontinuation. The only discontinuation phenomenon I experienced was insomnia, but not total insomnia. I was able to sleep, but my sleep was very broken and light for a few days.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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