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Re: Venlafaxine is not an SSRI beckett2

Posted by SLS on August 22, 2022, at 12:27:17

In reply to Re: Venlafaxine is not an SSRI Christ_empowered, posted by beckett2 on August 21, 2022, at 22:01:01

Hi, Beckett2


I hope you don't mind my asking you a few questions regarding ketamine:


1. What route do you use for taking ketamine?

2. What dosage are you taking?

3. How often do you take ketamine?

4. How long did it take for you to experience an improvement with ketamine?

5. Do you experience any dissociation immediately after taking ketamine?

6. What dosage of lamotrigine are you taking?

7. What brand of generic lamotrigine are you taking?



It makes a certain amount of sense to me that combining lamotrigine and ketamine would produce a synergy in reducing glutamatergic activity. Separately, both drugs reduce glutamate neural activity, albeit via different mechanisms.

1. Ketamine - NMDA glutamate receptor antagonist.

2. Lamotrigine - Glutamate release inhibition.


Beckett2 - Although this combination of drugs is working well for you to treat depression, it seems counterintuitive to me when taking into consideration the efficacy of lithium to treat depression literature when considering the many reports that low dosages of lithium

I tried intranasal ketamine. It had no effect on me, even at twice the recommended dose. I should have experienced some degree of dissociation, but I didn't. In retrospect, I think the compounding pharmacy might not have prepared the drug properly.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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