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Re: Auvelity (dextromethorphan and bupropion)

Posted by PeterMartin on August 21, 2022, at 0:18:47

In reply to Re: Auvelity (dextromethorphan and bupropion), posted by PeterMartin on August 21, 2022, at 0:14:24

Oh couple quick things from my experiences w/ Dextromethorphan:

Do -not- take it w/ an MAOi - there are reports in the literature of fatalities (one of the true -do not take- w/ an maoi contradictions).

Lamictal really blunted the effect for me. This is decades ago now, but when I was first introduced to dextromethorphan (as robitussin cold & cough) we'd use it to trip out similar to shrooming. Years later I was put on Lamictal and it totally blocked the tripping aspect. I'd still space out a bit, and feel very detached but happy/social and w/o anxiety....but it was significantly less intense.

So, from my experience, I'd expect this medication to be different, if not less effective, for those currently on Lamictal.




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