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Re: combining nardil and parnate ) SLS

Posted by SLS on April 1, 2022, at 10:08:46

In reply to Re: combining nardil and parnate ) SLS, posted by undopaminergic on April 1, 2022, at 3:54:18

> > True, you can also try Psychotherapy or lifestyle changes. Hope does not have to rely solely on new drugs. I only get excited when really new stuff comes out that does not go into the me-too category. Some meds are less 'me too' than others. Those are the ones that excite me. I would get excited for a Neuroleptic without metabolic side effects for example.
> >
> There are already neuroleptics with low risk of weight gain. In a nutshell, they are drugs without antihistamine effects. Examples are haloperidol and amisulpride.
> What would excite me more is antipsychotics without antidopaminergic effects.
> -undopaminergic

There certainly are neuroleptics that have a reduced incidence of weight-gain. However, it may be that none of those drugs make effective bridges to be used to reduce the intensity of withdrawal syndromes or preventing a full relapse.

A "bridge" is meant to be a temporary treatment to mitigate any suffering that occur during a washout period.

For me, I think there are 2 drugs that make good candidates tor being a bridges.

1. Zyprexa (olanzapine)
2. Saphris (asenapine)

Although Abilify (aripiprazole) might work well to mitigate an antidepressant withdrawal syndrome, discontinuing it is problematic and produces anxiety as its own withdrawal syndrome.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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