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Re: combining nardil and parnate

Posted by undopaminergic on March 25, 2022, at 12:56:37

In reply to Re: combining nardil and parnate rose45, posted by SLS on March 24, 2022, at 12:55:32

> I had a severe reaction to an accidental combination of Parnate + Nardil. My doctor was extremely aggressive, and didn't think there would be a problem with making a direct switch without a washout period.

That doesn't sound aggressive at all. There is no obvious reason to expect problems from going straight from one MAOI to another, because both have the same (primary) effect. Even taking into account the secondary effects of these two drugs, there is no reason to expect a dangerous interaction between Nardil's GABAergic effect and Parnate's amphetaminergic action; if anything, they would tend to cancel each other out.





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