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Fecal transplant in 2 bipolar patients

Posted by Hugh on March 17, 2022, at 12:08:29

In 2020, Russell Hinton, a private psychiatrist, described how he treated the first patient. This was a woman who had tried more than a dozen different medications for her bipolar. She had been hospitalized ten times, had gained considerable weight and judged she had no quality of life.

After a poo transplant from her husband, she became symptom-free over the next five years, lost 33 kilograms [72 pounds], required no medication and her career bloomed.

Gordon Parker and colleagues at the University of New South Wales reported their results with the second patient last month. This was a young man who developed bipolar as a teenager, had tried numerous medications and became progressively intolerant of their side effects.

After a poo transplant, he was able to progressively cease all medications over the next year, and had virtually no mood swings. He also noted an improvement in his anxiety and ADHD (attention deficit hyperactivity disorder).

Abnormal gut microbiomes have been linked to bipolar, depression and schizophrenia.

When poo from depressed humans is given to rats, they appear to develop a rat version of depression. Likewise, when mice are given poo from someone with schizophrenia, they develop a mouse version of schizophrenia.

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