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Re: Esmethadone helps treatment-resistant depression

Posted by PeterMartin on January 12, 2022, at 14:36:18

In reply to Re: Esmethadone helps treatment-resistant depression SLS, posted by Hugh on January 11, 2022, at 20:41:21

Where does Dextromethorphan fit in w/ these drugs that act on NMDA? I used to use it "recreationally" via cough syrup in the mid '00s and it was really good at helping my mood. In tandem w/ Lamotrigine I didn't "trip", but instead felt much more social and comfortable (removed depression/anxiety).

I've mentioned it a few times lately but AXS-05 (which is Dextromethorphan/Bupropion comb) seemed to do really well in phase 3 trials and should be approved by the end of the year.


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poster:PeterMartin thread:1118094
URL: http://www.dr-bob.org/babble/20211102/msgs/1118111.html